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Search results (498)

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TRX loss couples genome instability at a G-rich repeat to dysregulation of human alpha-globin expression.

Shen Y. et al, (2026), Nat Commun

Switching and Sniffing around the β-globin cluster.

Higgs D. and Gupta K., (2026), Blood, 147, 609 - 610

Mapping chromatin structure at base-pair resolution unveils a unified model of cis-regulatory element interactions.

Li H. et al, (2025), Cell, 188, 7175 - 7193.e19

ctive regulatory elements recruit cohesin to establish cell specific chromatin domains.

Georgiades E. et al, (2025), Sci Rep, 15

Identification of new candidate drugs in myelodysplastic syndromes with splicing factor mutations by transcriptional profiling and connectivity map analysis.

Sun T. et al, (2025), Br J Haematol, 206, 1086 - 1091

ncient genomic linkage of α-globin and Nprl3 couples metabolism with erythropoiesis.

Preston AE. et al, (2025), Nat Commun, 16

Correction: The α-globin super-enhancer acts in an orientation-dependent manner.

Kassouf MT. et al, (2025), Nat Commun, 16

The α-globin super-enhancer acts in an orientation-dependent manner.

Kassouf MT. et al, (2025), Nat Commun, 16

Erythropoiesis in the human

Higgs DR. et al, (2025), 43 - 55

The characteristics of CTCF binding sequences contribute to enhancer blocking activity.

Tsang FH. et al, (2024), Nucleic Acids Res, 52, 10180 - 10193

Hemoglobin Bart's hydrops fetalis: charting the past and envisioning the future.

Amid A. et al, (2024), Blood, 144, 822 - 833

Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes.

Xiang G. et al, (2024), Genome Res, 34, 1089 - 1105

Loss-of-Function Variants in SUPT5H as Modifying Factors in Beta-Thalassemia.

Harteveld CL. et al, (2024), Int J Mol Sci, 25

Developing a pill to treat sickle cell disease.

Higgs D. and Kassouf M., (2024), Science, 385, 27 - 28

Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes.

Xiang G. et al, (2024), bioRxiv

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