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Search results (22)

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Platelets sequester extracellular DNA, capturing tumor-derived and free fetal DNA.

Murphy L. et al, (2025), Science, 389

Selective Btk inhibition by PRN1008/PRN473 blocks human CLEC-2, and PRN473 reduces venous thrombosis formation in mice.

Smith CW. et al, (2024), Blood Adv, 8, 5557 - 5570

A proinflammatory stem cell niche drives myelofibrosis through a targetable galectin-1 axis.

Li R. et al, (2024), Sci Transl Med, 16

Generating human bone marrow organoids for disease modeling and drug discovery.

Olijnik A-A. et al, (2024), Nat Protoc, 19, 2117 - 2146

Restraining of glycoprotein VI- and integrin α2β1-dependent thrombus formation by platelet PECAM1.

Jooss NJ. et al, (2024), Cell Mol Life Sci, 81

Platelet glycoprotein VI cluster size is related to thrombus formation and phosphatidylserine exposure in collagen-adherent platelets under arterial shear.

Jooss NJ. et al, (2023), J Thromb Haemost, 21, 2260 - 2267

Pharmacological Inhibition of Glycoprotein VI- and Integrin α2β1-Induced Thrombus Formation Modulated by the Collagen Type.

Jooss NJ. et al, (2023), Thromb Haemost, 123, 597 - 612

Characterizing the binding of glycoprotein VI with nanobody 35 reveals a novel monomeric structure of glycoprotein VI where the conformation of D1+D2 is independent of dimerization.

Damaskinaki F-N. et al, (2023), J Thromb Haemost, 21, 317 - 328

A pro-inflammatory stem cell niche drives myelofibrosis through a targetable galectin 1 axis

Li R. et al, (2023)

CLEC-2 Supports Platelet Aggregation in Mouse but not Human Blood at Arterial Shear.

Bourne JH. et al, (2022), Thromb Haemost, 122, 1988 - 2000

Anti-GPVI nanobody blocks collagen- and atherosclerotic plaque-induced GPVI clustering, signaling, and thrombus formation.

Jooss NJ. et al, (2022), J Thromb Haemost, 20, 2617 - 2631

Roles of Focal Adhesion Kinase PTK2 and Integrin αIIbβ3 Signaling in Collagen- and GPVI-Dependent Thrombus Formation under Shear.

Huang J. et al, (2022), Int J Mol Sci, 23

Targeting platelet-derived CXCL12 impedes arterial thrombosis.

Leberzammer J. et al, (2022), Blood, 139, 2691 - 2705

MicroRNA-26b Attenuates Platelet Adhesion and Aggregation in Mice.

Peters LJF. et al, (2022), Biomedicines, 10

Platelets fine-tune effector responses of naïve CD4+ T cells via platelet factor 4-regulated transforming growth factor β signaling.

Min Y. et al, (2022), Cell Mol Life Sci, 79

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