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Search results (18)

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Menin maintains enhancer-promoter interactions in a leukemia-specific manner

Sharlandjieva V. et al, (2026)

A genome-wide screen identifies Runx2 as a novel regulator of hematopoietic stem cell expansion and T-cell commitment.

Meaker GA. et al, (2025), Blood, 146, 3188 - 3200

Enhancer heterogeneity in acute lymphoblastic leukemia drives differential gene expression in patients.

Smith AL. et al, (2025), Blood, 146, 2073 - 2087

PROM1/CD133 marks a proliferative stem cell-like population of blasts in KMT2A rearranged infant ALL.

Cross JW. et al, (2025), Blood Adv, 9, 4607 - 4613

Iron deficiency causes aspartate-sensitive dysfunction in CD8+ T cells.

Teh MR. et al, (2025), Nat Commun, 16

TRANCERs: Engineering enhancers into autonomous tissue-specific expression cassettes

Barrow Molina E. et al, (2025)

The Fetal Specific Gene LIN288 Is Essential for Human Fetal B-Lymphopoiesis and Initiation of KMT2A-AFF1+ Infant Acute Lymphoblastic Leukemia

Ling RE. et al, (2024), BLOOD, 144, 199 - 200

A human genome editing-based MLL::AF4 ALL model recapitulates key cellular and molecular leukemogenic features.

Bueno C. et al, (2023), Blood, 142, 1752 - 1756

Temporal analyses reveal a pivotal role for sense and antisense enhancer RNAs in coordinate immunoglobulin lambda locus activation.

Gao Z. et al, (2023), Nucleic Acids Res, 51, 10344 - 10363

Author Correction: Capture-C: a modular and flexible approach for high-resolution chromosome conformation capture.

Downes DJ. et al, (2023), Nat Protoc, 18

MLL-AF4 cooperates with PAF1 and FACT to drive high-density enhancer interactions in leukemia.

Crump NT. et al, (2023), Nat Commun, 14

Dysregulation of chromatin via H3K27 methylation underpins differentiation arrest in Isocitrate dehydrogenase-mutant Acute Myeloid Leukaemia

Silveira DRA. et al, (2023)

Sustained MYB Activity Is Necessary for Oncogenic Transcription in KMT2A-Rearranged Acute Lymphoblastic Leukemia through Enhancer-Promoter Interactions and Epigenetic Modifications at Enhancers

Lau J. et al, (2023), BLOOD, 142

Capture-C: a modular and flexible approach for high-resolution chromosome conformation capture.

Downes DJ. et al, (2022), Nat Protoc, 17, 445 - 475

Establishment and Characterization of a Model of Acquired Resistance to DOT1L Inhibition in KMT2A-Rearranged Acute Lymphoblastic Leukemia Cells

Schneider P. et al, (2022), BLOOD, 140, 8760 - 8761

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