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Search results (17)

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Clinical significance of preleukemic somatic GATA1 mutations in children with Down syndrome.

Elliott N. et al, (2025), Blood, 146, 1561 - 1574

RUNX1 loss renders hematopoietic and leukemic cells dependent on IL-3 and sensitive to JAK inhibition.

Fan AC. et al, (2023), J Clin Invest, 133

The Cell Type-Specific 5hmC Landscape and Dynamics of Healthy Human Hematopoiesis and TET2-Mutant Preleukemia.

Nakauchi Y. et al, (2022), Blood Cancer Discov, 3, 346 - 367

IL-3 SELECTIVELY RESCUES RUNX1-DEFICIENT HUMAN HSPCS WITH DYSREGULATED JAK/STAT SIGNALING

Fan A. et al, (2022), EXPERIMENTAL HEMATOLOGY, 111, S84 - S84

Oncogenic Gata1 causes stage-specific megakaryocyte differentiation delay.

Juban G. et al, (2021), Haematologica, 106, 1106 - 1119

HYPERSENSITIVITY TO IL-3 RESCUES INFLAMMATORY RUNX1-DEFICIENT HUMAN HSPCS

Fan A. et al, (2021), EXPERIMENTAL HEMATOLOGY, 100, S48 - S48

Sensitive, rapid diagnostic test for transient abnormal myelopoiesis and myeloid leukemia of Down syndrome.

Cruz Hernandez D. et al, (2020), Blood, 136, 1460 - 1465

Myeloid Pre-Leukemia and Leukemia of Down Syndrome

Cruz Hernandez D. and VYAS P., (2020), HemaSphere

GATA1 and cooperating mutations in myeloid leukaemia of Down syndrome.

Garnett C. et al, (2020), IUBMB Life, 72, 119 - 130

Oncogenic Drivers and Development.

Cruz Hernandez D. and Vyas P., (2019), Cancer Discov, 9, 1653 - 1655

Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome.

Labuhn M. et al, (2019), Cancer Cell, 36

Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome.

Labuhn M. et al, (2019), Cancer Cell, 36, 123 - 138.e10

MODELING THE PATHOGENESIS OF RUNX1 DEFICIENCY IN INHERITED AML PREDISPOSITION SYNDROMES IN PRIMARY CELLS

Fan A. et al, (2019), EXPERIMENTAL HEMATOLOGY, 76, S65 - S65

Generation and use of a humanized bone-marrow-ossicle niche for hematopoietic xenotransplantation into mice.

Reinisch A. et al, (2017), Nat Protoc, 12, 2169 - 2188

Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6.

Bak RO. et al, (2017), Elife, 6

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