Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Search results (36)

« Back to Publications

ssaying the myosin super-relaxed state across muscle types, cells and proteins for understanding muscle biology and use in drug discovery.

Jones STM. et al, (2025), Nat Protoc

Microscale droplet assembly enables biocompatible multifunctional modular iontronics.

Zhang Y. et al, (2024), Science, 386, 1024 - 1030

Hypertrophic cardiomyopathy-associated mutations drive stromal activation via EGFR-mediated paracrine signaling.

Ewoldt JK. et al, (2024), Sci Adv, 10

n ALPK3 truncation variant causing autosomal dominant hypertrophic cardiomyopathy is partially rescued by mavacamten

Leinhos L. et al, (2024)

Targeted genetic therapies for inherited disorders that affect both cardiac and skeletal muscle.

Psaras Y. and Toepfer CN., (2024), Exp Physiol, 109, 175 - 189

Comparing the effects of chemical Ca2+ dyes and R-GECO on contractility and Ca2+ transients in adult and human iPSC cardiomyocytes.

Robinson P. et al, (2023), J Mol Cell Cardiol, 180, 44 - 57

Mechanism based therapies enable personalised treatment of hypertrophic cardiomyopathy.

Margara F. et al, (2022), Sci Rep, 12

Pathogenesis of Cardiomyopathy Caused by Variants in ALPK3, an Essential Pseudokinase in the Cardiomyocyte Nucleus and Sarcomere.

Agarwal R. et al, (2022), Circulation, 146, 1674 - 1693

Cell cycle defects underlie childhood-onset cardiomyopathy associated with Noonan syndrome.

Meier AB. et al, (2022), iScience, 25

Plakophilin-2 truncating variants impair cardiac contractility by disrupting sarcomere stability and organization.

Zhang K. et al, (2021), Sci Adv, 7

Filamin C Cardiomyopathy Variants Cause Protein and Lysosome Accumulation.

Agarwal R. et al, (2021), Circ Res, 129, 751 - 766

CalTrack: High-Throughput Automated Calcium Transient Analysis in Cardiomyocytes.

Psaras Y. et al, (2021), Circ Res, 129, 326 - 341

Cardiac myosin super relaxation (SRX): a perspective on fundamental biology, human disease and therapeutics.

Schmid M. and Toepfer CN., (2021), Biol Open, 10

Future Leaders to Watch - Christopher Toepfer and Manuel Schmid

Toepfer C. and Schmid M., (2021), BIOLOGY OPEN, 10

GATA6 mutations in hiPSCs inform mechanisms for maldevelopment of the heart, pancreas, and diaphragm.

Sharma A. et al, (2020), Elife, 9

Load More