Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Search results (14)

« Back to Publications

Hypertrophic cardiomyopathy caused by Filamin-C (FLNC) variants has restrictive and extracardiac features and a distinctive ECG.

de Villiers C. et al, (2026), Heart Rhythm

Nutraceuticals silybin B, resveratrol, and epigallocatechin-3 gallate-bind to cardiac muscle troponin to restore the loss of lusitropy caused by cardiomyopathy mutations in vitro, in vivo, and in silico.

Yang Z. et al, (2024), Front Physiol, 15

Calcitonin signalling system regulates function and arhythmogenicity of atrial cardiomyocytes

Moreira L. et al, (2024), EUROPEAN HEART JOURNAL, 45

Modulating TTN gene expression in human iPSC-CMs to investigate mechanisms and therapies in TTN-associated dilated cardiomyopathy

Kirk RB. et al, (2024), EUROPEAN HEART JOURNAL, 45

Comparing the effects of chemical Ca2+ dyes and R-GECO on contractility and Ca2+ transients in adult and human iPSC cardiomyocytes.

Robinson P. et al, (2023), J Mol Cell Cardiol, 180, 44 - 57

CalTrack: High-Throughput Automated Calcium Transient Analysis in Cardiomyocytes.

Psaras Y. et al, (2021), Circ Res, 129, 326 - 341

Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia.

Moreira LM. et al, (2020), Nature, 587, 460 - 465

Dilated cardiomyopathy mutations in thin-filament regulatory proteins reduce contractility, suppress systolic Ca2+, and activate NFAT and Akt signaling.

Robinson P. et al, (2020), Am J Physiol Heart Circ Physiol, 319, H306 - H319

Mavacamten rescues increased myofilament calcium sensitivity and dysregulation of Ca2+ flux caused by thin filament hypertrophic cardiomyopathy mutations.

Sparrow AJ. et al, (2020), Am J Physiol Heart Circ Physiol, 318, H715 - H722

Measurement of Myofilament-Localized Calcium Dynamics in Adult Cardiomyocytes and the Effect of Hypertrophic Cardiomyopathy Mutations.

Sparrow AJ. et al, (2019), Circ Res, 124, 1228 - 1239

Hypertrophic cardiomyopathy mutations increase myofilament Ca2+ buffering, alter intracellular Ca2+ handling, and stimulate Ca2+-dependent signaling.

Robinson P. et al, (2018), J Biol Chem, 293, 10487 - 10499

LIM kinase function and renal growth: Potential role for LIM kinases in fetal programming of kidney development.

Sparrow AJ. et al, (2017), Life Sci, 186, 17 - 24

cetylsalicylic acid interferes with embryonic kidney growth and development by a prostaglandin-independent mechanism.

Welham SJM. et al, (2017), World J Nephrol, 6, 21 - 28

Excess maternal salt intake produces sex-specific hypertension in offspring: putative roles for kidney and gastrointestinal sodium handling.

Gray C. et al, (2013), PLoS One, 8