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Wireless left ventricular endocardial pacing with the WiSE CRT system has recently become available as alternative to conventional epicardial CRT pacing. We report the first comparison of the acute electrical and hemodynamic response produced by the two CRT pacing modalities in a patient undergoing WiSE CRT implant after a failed conventional CRT procedure. WiSE CRT pacing showed an additive acute benefit compared with conventional CRT. These findings could potentially translate into long-term clinical benefit and introduce the potential for tri-ventricular pacing using both systems simultaneously.

Original publication




Journal article


J Arrhythm

Publication Date





87 - 89


acute hemodynamic response, cardiac resynchronization therapy, heart failure, left ventricular endocardial stimulation, left ventricular epicardial stimulation