Increasing value and reducing waste in stroke research.
Berge E., Al-Shahi Salman R., van der Worp HB., Stapf C., Sandercock P., Sprigg N., Macleod MR., Kelly PJ., Nederkoorn PJ., Ford GA., European Stroke Organisation Trials Network Committee None.
Stroke is a major burden to patients and society, and resources spent on stroke research must be used efficiently and produce good value in terms of improvements in human health. However, many instances of poor value from stroke research funding have resulted from the way in which stroke research topics have been chosen and how studies have been designed, conducted, analysed, regulated, managed, disseminated, or reported. A cooperative effort of European stroke researchers aimed to identify sources of inefficiency and waste, recommend approaches to increase value, and highlight examples of best practice in stroke research. Evidence suggests that progress has been made, but there is room for much improvement; researchers, funders, regulators, and other stakeholders in stroke research might consider these recommendations when planning new research.