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Mechanisms of stabilization of the vascular plexus and the role of mechanotransduction in this process are not well understood. In this issue of Developmental Cell, Jung et al. (2012) and Gaengel et al. (2012) describe the ligand-sensitive and mechanosensitive functions of an important vascular G protein-coupled receptor, S1P1.

Original publication

DOI

10.1016/j.devcel.2012.08.012

Type

Journal article

Journal

Dev Cell

Publication Date

11/09/2012

Volume

23

Pages

451 - 452