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Trisomy 10 is a rare nonrandom cytogenetic abnormality found in association with acute myeloid leukemia (AML). The hematological and clinical features associated with this finding have not yet been clearly defined. A literature review revealed 13 cases of trisomy 10 in AML, some reported as a minority component of a more comprehensive AML study and therefore lacking a full description of both clinical and hematological features. We present a summary of these reports and add three new cases to the literature.

Original publication

DOI

10.1016/s0165-4608(99)00134-x

Type

Journal article

Journal

Cancer Genet Cytogenet

Publication Date

15/04/2000

Volume

118

Pages

148 - 150

Keywords

Acute Disease, Adult, Chromosomes, Human, Pair 10, Female, Humans, Leukemia, Myeloid, Male, Middle Aged, Trisomy