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Fibroblast growth factors were first characterized twenty years ago as mitogens of cultured fibroblasts. Despite a wealth of data from experiments in vitro, insights have begun to emerge only recently on the normal function of these growth factors in mice and humans, as a result of studies of natural and experimental mutations in the factors and their receptors.

Type

Journal article

Journal

Curr biol

Publication Date

01/05/1995

Volume

5

Pages

500 - 507

Keywords

Amino Acid Sequence, Animals, Fibroblast Growth Factors, Humans, Ligands, Molecular Sequence Data, Mutation, Protein Conformation, Receptors, Fibroblast Growth Factor