Contemporary Approach to the Diagnosis and Classification of Myelodysplastic Neoplasms/Syndromes-Recommendations From the International Consortium for Myelodysplastic Neoplasms/Syndromes (MDS [icMDS]).
Aakash F., Gisriel SD., Zeidan AM., Bennett JM., Bejar R., Bewersdorf JP., Borate UM., Boultwood J., Brunner AM., Buckstein R., Carraway HE., Churpek JE., Daver NG., DeZern AE., Efficace F., Fenaux P., Figueroa ME., Garcia-Manero G., Gore SD., Greenberg PL., Griffiths EA., Halene S., Hourigan CS., Kim TK., Kim N., Komrokji RS., Kutchroo VK., List AF., Little RF., Majeti R., Nazha A., Nimer SD., Odenike O., Padron E., Patnaik MM., Platzbecker U., Della Porta MG., Roboz GJ., Sallman DA., Santini V., Sanz G., Savona MR., Sekeres MA., Stahl M., Starczynowski DT., Steensma DP., Taylor J., Abdel-Wahab O., Wei AH., Xie Z., Xu ML., Hasserjian RP., Loghavi S.
Myelodysplastic neoplasms/syndromes (MDS) are a heterogeneous group of biologically distinct entities characterized by variable degrees of ineffective hematopoiesis. Recently, 2 classification systems (the 5th edition of the World Health Organization Classification of Haematolymphoid tTumours and the International Consensus Classification) further subcharacterized MDS into morphologically and genetically defined groups. Accurate diagnosis and subclassification of MDS require a multistep systemic approach. The International Consortium for MDS (icMDS) summarizes a contemporary, practical, and multimodal approach to MDS diagnosis and classification.