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We describe a young boy with severe haemophilia B who developed inhibitory antibodies and an anaphylactoid reaction to factor IX. Immune tolerance was achieved by desensitisation with escalating doses of factor IX followed by the Malmö regimen.

Original publication

DOI

10.1111/j.1365-2516.2007.01463.x

Type

Journal article

Journal

Haemophilia

Publication Date

05/2007

Volume

13

Pages

328 - 330

Keywords

Anaphylaxis, Antibodies, Child, Preschool, Drug Administration Schedule, Factor IX, Hemophilia B, Humans, Immune Tolerance, Male, Treatment Outcome