Radcliffe Department of Medicine

Loss of cellular RNA homeostasis contributes to MDA5 activation during virus infection.

Sampaio NG. et al, (2026), Nat Immunol

α-Synuclein blocks endoplasmic reticulum co-translational protein translocation early in Parkinson's disease.

Lam CL. et al, (2026), Nat Commun, 17

Rapid glycolytic metabolism underpins mucosal-associated invariant T cell functional responses to innate cytokines.

Ryan EK. et al, (2026), J Immunol, 215

Impaired Metabolic Remodeling Characterizes Injured Niches during Post-ischemic Kidney Repair

Rietjens RGJ. et al, (2026), Journal of the American Society of Nephrology

Gut microbiota restricts intestinal lipid uptake via modulation of bile phosphatidylcholine metabolism in mice.

Brunner S. et al, (2026), Nat Microbiol, 11, 2349 - 2364

Enforcing mTORC1 activity in therapeutic CD4+ T cells promotes persistence but eventual immune exhaustion.

Sillito F. et al, (2026), Journal of immunology (Baltimore, Md. : 1950), 215

The Thrombopoietin Receptor S264F Mutant Drives MPN with Marrow Fibrosis Through a Dual Mechanism

MEAD A., (2026), HemaSphere

Resolving hematopoietic stem versus progenitor cell potential in the mouse dorsal aorta by differential Runx1 +110 enhancer activity.

Anselmi G. et al, (2026), Cell Rep, 45

Nucleophagy as an emerging therapeutic vulnerability in cancer.

Tribble S. and Ramadan K., (2026), Autophagy, 1 - 3

The effect of cohesin mutations on HLA-class II expression in the myeloid leukemia of Down syndrome.

Boucher AC. et al, (2026), Leukemia

Identification and masking of artefactual and misleading within-host variants in deep-sequencing SARS-CoV-2 data.

Anker K. et al, (2026), Molecular Biology and Evolution (MBE)

Identification of a novel deeply quiescent neural stem cell population in the subventricular zone: a potential source for brain repair.

Nath AR. et al, (2026), Cell Discov, 12

The challenge and promise of studying human antigen-specific T cells.

Farrar S. et al, (2026), Nat Rev Immunol

Magrolimab Plus Azacitidine Versus Placebo Plus Azacitidine in Patients With Untreated Higher-Risk Myelodysplastic Syndromes: The Phase III ENHANCE Study.

Sallman DA. et al, (2026), J Clin Oncol

Transcriptomic analysis of tissue-resident memory T cells of the fallopian tube reveals a precursor immune surveillance network for ovarian cancer prevention.

Wang L. et al, (2026), Nat Commun

Immunology of pregnancy and sepsis: shared and specific pathways guiding future precision care.

Amarasinghe HE. et al, (2026), EBioMedicine, 130

Thalassaemia.

Piel FB. et al, (2026), Nat Rev Dis Primers, 12

Forging New Pathways in Oncology: Strategic Insights from the 17th Annual Frontiers in Cancer Science Conference.

Huang D. et al, (2026), Cancer Res, 86, 3106 - 3108

CDIN1-Codanin-1 complex defective in congenital dyserythropoietic anaemia type I is an RNA nuclease.

Brolih S. et al, (2026), Nat Commun

CAR T cell therapy selectively depletes disease-driving mutant calreticulin cells in xenotransplants and human organoid models of myelofibrosis.

Rampotas A. et al, (2026), Sci Transl Med, 18

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