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Cancer stem cells may be important targets for new anticancer drugs. In two recent articles in Cell Stem Cell, Jin et al. (2009) and Hoey et al. (2009) provide proof of principle for this idea in experimental models of solid tumors and leukemias, respectively.

Original publication

DOI

10.1016/j.stem.2009.07.006

Type

Journal article

Journal

Cell Stem Cell

Publication Date

07/08/2009

Volume

5

Pages

125 - 126

Keywords

Animals, Antibodies, Monoclonal, Antineoplastic Agents, Humans, Interleukin-3 Receptor alpha Subunit, Intracellular Signaling Peptides and Proteins, Membrane Proteins, Mice, Neoplasms, Neoplastic Stem Cells, Receptors, Notch