Adaptive islet biology and comprehensive incretin physiology: Emerging perspectives from Asia and Europe.
Murakami T., Nasteska D., Hodson DJ., Yamazaki Y., Yabe D., Seino Y.
Adaptive islet biology and incretin physiology provide a framework linking diverse diabetes phenotypes, with advances in β-cell stress adaptation, intra-islet communication, receptor-resolved biology, and β-cell mass imaging. By integrating clinical perspectives from Asia and Europe with multiscale islet-cell biology, these insights may support mechanism-based and more targeted therapeutic approaches.