Circadian variability in breath volatiles is affected by the timing of inhaled corticosteroids in asthma.
Wang R., Maidstone R., Ahmed W., Singh D., Ray D., Loudon A., Simpson A., Fowler SJ., Durrington HJ.
Dosage timings of inhaled corticosteroids and time of day are both important confounders for exhaled VOC levels in asthma. These factors must be appropriately accounted for at the biomarker discovery stage, allowing for external validation of findings. https://bit.ly/435BQtt.