COVID-19, plasma, and hypogammaglobulinemia.
Murphy MF., Dzik S.
In this issue of Blood, Hueso et al report a study of COVID-19 convalescent plasma (CCP) in patients with COVID-19 and negative severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serology with severe immunodeficiency due to prior treatment with anti-CD20 monoclonal antibodies. The study reports on the safety and efficacy of COVID-19 CCP in 17 patients with profound B-cell lymphopenia and protracted COVID-19 disease.