Publications — Radcliffe Department of Medicine

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Genetic Predisposition to Type 2 Diabetes and Risk of Subclinical Atherosclerosis and Cardiovascular Diseases Among 160,000 Chinese Adults.

Gan W. et al, (2019), Diabetes, 68, 2155 - 2164

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology.

Spracklen CN. et al, (2019), Am J Hum Genet, 105, 670 - 671

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration.

Liu X. et al, (2019), Nat Commun, 10

ZRANB3 is an African-specific type 2 diabetes locus associated with beta-cell mass and insulin response.

Adeyemo AA. et al, (2019), Nat Commun, 10

Genome-wide association study of type 2 diabetes in Africa.

Chen J. et al, (2019), Diabetologia, 62, 1204 - 1211

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.

Flannick J. et al, (2019), Nature, 570, 71 - 76

Variation in the Plasma Membrane Monoamine Transporter (PMAT) (Encoded by SLC29A4) and Organic Cation Transporter 1 (OCT1) (Encoded by SLC22A1) and Gastrointestinal Intolerance to Metformin in Type 2 Diabetes: An IMI DIRECT Study.

Dawed AY. et al, (2019), Diabetes Care, 42, 1027 - 1033

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.

Warrington NM. et al, (2019), Nat Genet, 51, 804 - 814

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

MCCARTHY MARK., (2019), Nature Genetics

Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases.

Sanna S. et al, (2019), Nat Genet, 51, 600 - 605

Developing a network view of type 2 diabetes risk pathways through integration of genetic, genomic and functional data.

Fernández-Tajes J. et al, (2019), Genome Med, 11

The Genetic Basis of Metabolic Disease.

Barroso I. and McCarthy MI., (2019), Cell, 177, 146 - 161

Dissecting features of epigenetic variants underlying cardiometabolic risk using full-resolution epigenome profiling in regulatory elements.

Allum F. et al, (2019), Nat Commun, 10

Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.

Rhodes CJ. et al, (2019), Lancet Respir Med, 7, 227 - 238

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.

Justice AE. et al, (2019), Nat Genet, 51, 452 - 469

The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects.

Middeldorp CM. et al, (2019), Eur J Epidemiol, 34, 279 - 300

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

McCarthy M., (2019), Nature Genetics

A novel rare CUBN variant and three additional genes identified in Europeans with and without diabetes: results from an exome-wide association study of albuminuria.

Ahluwalia TS. et al, (2019), Diabetologia, 62, 292 - 305

Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control.

Pollack S. et al, (2019), Diabetes, 68, 441 - 456

Plasma Fucosylated Glycans and C-Reactive Protein as Biomarkers of HNF1A-MODY in Young Adult-Onset Nonautoimmune Diabetes.

Juszczak A. et al, (2019), Diabetes Care, 42, 17 - 26

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