Publications — Radcliffe Department of Medicine

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Preclinical drug studies in MEN1-related neuroendocrine neoplasms (MEN1-NENs).

Grozinsky-Glasberg S. et al, (2020), Endocr Relat Cancer

Genetic background influences tumour development in heterozygous Men1 knockout mice.

Lines KE. et al, (2020), Endocr Connect, 9, 426 - 437

Clinical MEN-1 among a large cohort of patients with acromegaly.

Nachtigall LB. et al, (2020), J Clin Endocrinol Metab

MEN1-related PanNETs: identifying unmet clinical needs and future directives.

Pieterman CRC. et al, (2020), Endocr Relat Cancer

Effects of epigenetic pathway inhibitors on corticotroph tumour AtT20 cells

LINES K. et al, (2020), Endocrine-Related Cancer

Whole genome sequence analysis identifies a PAX2 mutation to establish a correct diagnosis for a syndromic form of hyperuricemia

Stevenson M. et al, (2020), American Journal of Medical Genetics, Part A

Activating mutations of the G-protein subunit α11 interdomain interface cause autosomal dominant hypocalcemia type 2.

Gorvin CM. et al, (2019), J Clin Endocrinol Metab

Large-Scale Sequence Database Analyses Reveals 5 novel GNA11 mutations that alter Calcium-Sensing-Receptor Signalling: Relevance for FHH2 and ADH2

Gluck A. et al, (2019), JOURNAL OF BONE AND MINERAL RESEARCH, 34, 321 - 321

Large-Scale Sequence Database Analyses Reveals 5 novel GNA11 mutations that alter Calcium-Sensing-Receptor Signalling: Relevance for FHH2 and ADH2

Gluck A. et al, (2019), JOURNAL OF BONE AND MINERAL RESEARCH, 34, 321 - 321

Epigenetic dysregulation in pituitary tumors

Shariq OA. and Lines KE., (2019), International Journal of Endocrine Oncology

TWO SYNCHRONOUS PITUITARY ADENOMAS CAUSING CUSHING DISEASE AND ACROMEGALY.

Schorr M. et al, (2019), AACE Clin Case Rep, 5, e276 - e281

Association of prolactin receptor (PRLR) variants with prolactinomas.

Gorvin CM. et al, (2019), Hum Mol Genet, 28, 1023 - 1037

MiR-15a/miR-16-1 expression inversely correlates with cyclin D1 levels in Men1 pituitary NETs.

Lines KE. et al, (2018), J Endocrinol

Molecular Genetic Studies of Pancreatic Neuroendocrine Tumors: New Therapeutic Approaches.

Stevenson M. et al, (2018), 47, 525 - 548

Current and emerging therapies for PNETs in patients with or without MEN1.

Frost M. et al, (2018), Nat Rev Endocrinol, 14, 216 - 227

Mice deleted for cell division cycle 73 gene develop parathyroid and uterine tumours: model for the hyperparathyroidism-jaw tumour syndrome.

Walls GV. et al, (2017), Oncogene, 36, 4025 - 4036

Epigenetic pathway inhibitors represent potential drugs for treating pancreatic and bronchial neuroendocrine tumors.

Lines KE. et al, (2017), Oncogenesis, 6

A MEN1 pancreatic neuroendocrine tumour mouse model under temporal control.

Lines KE. et al, (2017), Endocr Connect, 6, 232 - 242

Pasireotide Therapy of Multiple Endocrine Neoplasia Type 1-Associated Neuroendocrine Tumors in Female Mice Deleted for an Men1 Allele Improves Survival and Reduces Tumor Progression.

Walls GV. et al, (2016), Endocrinology, 157, 1789 - 1798

Animal models of pituitary neoplasia.

Lines KE. et al, (2016), Mol Cell Endocrinol, 421, 68 - 81

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