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Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds.

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Cruz-Migoni A. et al, (2019), Proc Natl Acad Sci U S A, 116, 2545 - 2550

Chemical Instability and Promiscuity of Arylmethylidenepyrazolinone-Based MDMX Inhibitors.

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From intracellular antibody fragments to small molecule inhibitors of mutant KRAS

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Thiazolidine derivatives as potent and selective inhibitors of the PIM kinase family.

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Using a Novel Combinatorial Non-Viral Vector and Small Molecules to Treat Familial Hypercholesterolaemia (FH)

Conference paper

Kerr AG. et al, (2016), MOLECULAR THERAPY, 24, S9 - S10

Exploring the surfaceome of Ewing sarcoma identifies a new and unique therapeutic target.

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Town J. et al, (2016), Proc Natl Acad Sci U S A, 113, 3603 - 3608

Ligand-based virtual screening identifies a family of selective cannabinoid receptor 2 agonists.

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Ligand-based virtual screening identifies a family of selective cannabinoid receptor 2 agonists

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Gianella-Borradori M. et al, (2014), Bioorganic and Medicinal Chemistry

Identification of new chemical compounds with upregulate utrophin for the therapy of Duchenne muscular dystrophy

Conference paper

Fairclough RJ. et al, (2012), NEUROMUSCULAR DISORDERS, 22, S3 - S3

Hydrogen-bonding-mediated directed osmium dihydroxylation

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Donohoe TJ. et al, (2011), Organic Reactions, 76, 1 - 48

Osmium-free direct syn-dihydroxylation of alkenes.

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Synthesis of (-)-hygromycin A: application of Mitsunobu glycosylation and tethered aminohydroxylation.

Journal article

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