From the dish to humans: A stem cell recipe for success.

Russ HA., Shilleh AH., Sussel L.

Islet transplantation has proven to be an effective treatment for type 1 diabetes (T1D) yet is hampered by the shortage of available tissue. Recently, two reports from a Viacyte multicenter clinical trial demonstrate the feasibility, safety, and potential efficacy of transplanting macro-encapsulated human stem cell-derived pancreatic endoderm cells into patients with T1D, highlighting the promise of a stem cell-based therapeutic approach.

DOI

10.1016/j.cmet.2022.01.002

Type

Journal article

Publication Date

2022-02-01T00:00:00+00:00

Volume

34

Pages

193 - 196

Total pages

3

Keywords

Cell Differentiation, Diabetes Mellitus, Type 1, Endoderm, Humans, Islets of Langerhans Transplantation, Stem Cells

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