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Earlier patient access to beneficial therapeutics that addresses unmet need is one of the main requirements of innovation in global healthcare systems already burdened by unsustainable budgets. "Adaptive pathways" encompass earlier cross-stakeholder engagement, regulatory tools, and iterative evidence generation through the life cycle of the medicinal product. A key enabler of earlier patient access is through more flexible and adaptive payer approaches to pricing and reimbursement that reflect the emerging evidence generated.

Original publication

DOI

10.1002/cpt.508

Type

Journal article

Journal

Clin Pharmacol Ther

Publication Date

12/2016

Volume

100

Pages

730 - 742

Keywords

Budgets, Costs and Cost Analysis, Delivery of Health Care, Diffusion of Innovation, European Union, Health Services Accessibility, Health Services Needs and Demand, Humans, Reimbursement Mechanisms, Time Factors, United States