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After several years of uncertain progress, the stage is now set for a transformation in understanding the genetic landscape of type 2 diabetes. Advances in genome informatics, genotyping technology, and statistical methodology, allied to availability of large-scale clinical material, are having a salutary effect on susceptibility gene discovery. The advent of genuinely genome-wide association scans and the prospects for combining genetics with high-throughput genomics are additional sources of optimism for the future.

Type

Journal article

Journal

Curr Diab Rep

Publication Date

04/2006

Volume

6

Pages

147 - 154

Keywords

Diabetes Mellitus, Type 2, Genetic Linkage, Genetic Research, Humans, PPAR gamma, Potassium Channels, Inwardly Rectifying, Proteins, Research Design