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The human immunoglobulin heavy chain gene complex has been assigned to chromosome 14 by filter hybridization of restriction digests of mouse-human somatic cell hybrids. Cloned DNA probes for both variable and constant regions were used.

Type

Journal article

Journal

Ann Hum Genet

Publication Date

10/1981

Volume

45

Pages

331 - 335

Keywords

Animals, Chromosome Mapping, Chromosomes, Human, 13-15, Humans, Hybrid Cells, Hybridization, Genetic, Immunoglobulin Heavy Chains, Karyotyping, Mice