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A new polymorphic BgI II restriction endonuclease site in the alpha-globin gene complex has been found in Cypriot, Sardinian, and Greek populations. In all cases, this polymorphism is linked to a particular hypervariable region between the zeta 2 and zeta 1 genes. This suggests that these hypervariable regions are stable and will be useful for genetic analysis.


Journal article


American journal of human genetics

Publication Date





1086 - 1089


Chromosomes, Human, 16-18, Humans, DNA Restriction Enzymes, Deoxyribonucleases, Type II Site-Specific, Globins, DNA, Chromosome Mapping, Homozygote, Polymorphism, Genetic, Genes, Greece, Italy, Cyprus