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OBJECTIVE: The cardiovascular consequences of the metabolic syndrome and its component risk factors have been documented in elderly individuals. Little is known about how the metabolic syndrome and its individual components translate into long-term medical costs. RESEARCH DESIGN AND METHODS: We used log-linear regression models to assess the independent contributions of the metabolic syndrome and its individual components to 10-year medical costs among 3,789 individuals aged > or = 65 years in the Cardiovascular Health Study. RESULTS: As defined by the National Cholesterol Education Program Third Adult Treatment Panel report, the metabolic syndrome was present in 47% of the sample. Total costs to Medicare were 20% higher among participants with the metabolic syndrome ($40,873 vs. $33,010; P < 0.001). Controlling for age, sex, race/ethnicity, and other covariates, we found that abdominal obesity, low HDL cholesterol, and elevated blood pressure were associated with 15% (95% CI 4.3-26.7), 16% (1.7-31.8), and 20% (10.1-31.7) higher costs, respectively. When added to the model, the metabolic syndrome composite variable did not contribute significantly (P = 0.32). CONCLUSIONS: Abdominal obesity, low HDL cholesterol, and hypertension but not the metabolic syndrome per se are important predictors of long-term costs in the Medicare population.

Original publication

DOI

10.2337/dc07-0460

Type

Journal article

Journal

Diabetes Care

Publication Date

10/2007

Volume

30

Pages

2553 - 2558

Keywords

Aged, Aged, 80 and over, Cholesterol, HDL, Continental Population Groups, Cost of Illness, Diabetic Angiopathies, Female, Humans, Hypertension, Interviews as Topic, Male, Medicare, Metabolic Syndrome, Multivariate Analysis, Obesity, Patient Education as Topic, Prospective Studies, Regression Analysis, United States