Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

There are now >30 antiretroviral medications available for the treatment of HIV. These drugs have distinct sites of action in the HIV life cycle, and unique pharmacological properties that dictate how they can be used safely in the treatment of HIV. Drug–drug interactions (DDIs) can occur because of alterations to several pharmacodynamic processes, including absorption and drug transport, but hepatic metabolism is clinically the most important. Co-administration of antiretrovirals with other, more commonly used drugs is commonplace, and clinicians must be aware of potential serious interactions that can lead to treatment failure and/or drug toxicity.

Original publication

DOI

10.1016/j.mpmed.2022.01.006

Type

Journal article

Journal

Medicine (United Kingdom)

Publication Date

01/04/2022

Volume

50

Pages

220 - 227