Glass yttrium-90 microspheres for patients with colorectal liver metastases.
Anderson JH., Goldberg JA., Bessent RG., Kerr DJ., McKillop JH., Stewart I., Cooke TG., McArdle CS.
Total calculated uniform liver doses of up to 150 Gy were achieved using glass yttrium-90 microspheres administered via the hepatic artery and targeted to tumour using angiotensin II in seven patients with colorectal liver metastases. No toxicity was observed. Hepatic metastatic progression was delayed in six patients. Median survival was 11 months (range 5-25 + months).