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Yue Du

Postdoctoral Research Scientist

I am currently a postdoctoral researcher working in the Gene Medicine group. Funded by the Wellcome Trust, my project is centred around investigating lentiviral and AAV-based gene delivery to the airway for the expression of monoclonal antibodies, in particular broadly neutralising antibodies, with an aim to confer a broad and long-term immunisation against Influenza, COVID-19, and other respiratory diseases.

Prior to this, I studied animal genetic engineering at the Roslin Institute, University of Edinburgh. During my PhD project, I utilised CRISPR/Cas9-mediated genome editing to investigate innovative strategies to reduce Influenza A Virus entry in pigs without compromising their immune responses. I obtained my Master’s degree in Animal Embryo Engineering from the Northwest A&F University, China. During my master’s study, I established a sperm-borne small RNA library for cattle and characterised the functional roles of sperm-specific miRNAs in embryo development. My past experience has laid me a solid and broad foundation in clinical veterinary medicine, developmental biology, and animal genetic engineering. As a natural progression, now I am particularly keen on developing novel passive immunotherapy for Influenza and participating in translational research.