Novo Nordisk Postdoctoral Research Fellow (2019-2021)
- Project: The role of ACVR1C signalling in human fat distribution.
Xuelu was awarded a Novo Nordisk Postdoctoral Fellowship in 2019, working with Professor Fredrik Karpe and Dr Constantinos Christodoulides in Oxford Centre for Diabetes, Endocrinology, and Metabolism. During her fellowship, Xuelu characterised the functional effects of ACVR1C deficiency on human depot-specific adipocytes, using both constitutive and acute knockdown cell models. She also used cell-based assays to analyse the activity of ACVR1C mutants related to healthy metabolic profiles and revealed detailed phenotypes of mutant carriers in the Oxford BioBank.
Following her fellowship, Xuelu has taken a position as Senior Scientist at AstraZeneca where she will apply her cell biology and protein science skills for the design and development of therapeutic macromolecules.