My current research is focused on using large-scale genetic data such as T2D-GENES /GoT2D/DIAGRAM Consortium, UK Biobank and China Kadoorie Biobank obtained from next-generation sequencing and GWAS approaches to 1) identify and characterise genetic variants influencing predisposition to type 2 diabetes and its related traits; 2) investigate the causal relationship between an exposure or intermediate phenotype and type 2 diabetes/cardiovascular diseases using Mendelian randomisation approaches; 3) identify genetic factors contributing to weight loss after bariatric surgery procedures.
I received my Ph.D degree at the Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences. In 2014, I joined Professor Mark McCarthy's group as postdoc researcher. I'm now also collaborating with Prof Rachel Batterham at UCLH and Professor Zhengming Chen at CTSU, Oxford University.
Genetic Predisposition to Type 2 Diabetes and Risk of Subclinical Atherosclerosis and Cardiovascular Diseases Among 160,000 Chinese adults.
Gan W. et al, (2019), Diabetes
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Turcot V. et al, (2019), Nat Genet, 51, 1191 - 1192
Inverse Relationship Between Coarse Food Grain Intake and Blood Pressure Among Young Chinese Adults.
Liu X. et al, (2019), Am J Hypertens, 32, 402 - 408
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.
Justice AE. et al, (2019), Nat Genet, 51, 452 - 469
The independent associations of protein consumption with body fat and glycaemic control in adult Chinese.
Liu X. et al, (2018), Eur J Nutr