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- McCarthy Group: Type 2 Diabetes Genetics and Genomics Research Group
My current research is focused on using large-scale genetic data such as T2D-GENES /GoT2D/DIAGRAM Consortium, UK Biobank and China Kadoorie Biobank obtained from next-generation sequencing and GWAS approaches to 1) identify and characterise genetic variants influencing predisposition to type 2 diabetes and its related traits; 2) investigate the causal relationship between an exposure or intermediate phenotype and type 2 diabetes/cardiovascular diseases using Mendelian randomisation approaches; 3) identify genetic factors contributing to weight loss after bariatric surgery procedures.
I received my Ph.D degree at the Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences. In 2014, I joined Professor Mark McCarthy's group as postdoc researcher. I'm now also collaborating with Prof Rachel Batterham at UCLH and Professor Zhengming Chen at CTSU, Oxford University.
Cannabis use and risk of schizophrenia: a Mendelian randomization study.
Vaucher J. et al, (2017), Mol Psychiatry
Evaluation of type 2 diabetes genetic risk variants in Chinese adults: findings from 93,000 individuals from the China Kadoorie Biobank.
Gan W. et al, (2016), Diabetologia, 59, 1446 - 1457
Rare and low-frequency coding variants alter human adult height.
Marouli E. et al, Nature, 542, 186 - 190