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Tao Dong


Professor of Immunology

  • Founding Director of CAMS-Oxford Centre for Translational Immunology

The main objective of my group’s research is to focus on the functional aspects of the antigen specific T cells and study the factors affecting T cells in controlling virus infection and cancer development.

For important human infections, cancer development and the course of disease is influenced mainly by the T cell response - while a robust and appropriate T cell response is beneficial to the host, a weak or inappropriate response can be ineffective or even have a detrimental effect. Numerous factors influence the quality of the T cell response to viral infections, predominant among them being the microenvironment of the infection site, the type of cells infected and the variability of the virus. By understanding the key factors required for efficient viral control by the T cell response in a number of different viral infections and viral associated cancer, we aim to augment and control the immune response to as a way of improving the outcome of in several important human diseases. Our current research program aims:

  • To define the impact of IFTIM3 genetic variation on Influenza, and other virus infection, immune responses and disease outcome
  • To study the Viral OncoProtein(VOP) and Tumor Specific Protein(TSP) specific T cell responses in virus associated cancer (ie HBV/HCC; EBV/NPC and HPV/CC)
  • To identify the factors determining functional avidity and anti-viral/cancer efficacy of antigen specific T cells in cancer micro-environment
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Selected Publications

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Recent Publications

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