Endothelial GTPCH (GTP Cyclohydrolase 1) and Tetrahydrobiopterin Regulate Gestational Blood Pressure, Uteroplacental Remodeling, and Fetal Growth.

Chuaiphichai S., Yu GZ., Tan CMJ., Whiteman C., Douglas G., Dickinson Y., Drydale EN., Appari M., Zhang W., Crabtree MJ., McNeill E., Hale AB., Lewandowski AJ., Alp NJ., Vatish M., Leeson P., Channon KM.

[Figure: see text].

DOI

10.1161/HYPERTENSIONAHA.120.17646

Type

Journal article

Publication Date

2021-12-01T00:00:00+00:00

Volume

78

Pages

1871 - 1884

Total pages

13

Keywords

biopterin, blood pressure, endothelial cells, pregnancy, vascular remodeling, Animals, Biopterins, Blood Pressure, Endothelial Cells, Endothelium, Vascular, Extracellular Vesicles, Female, Fetal Development, GTP Cyclohydrolase, Humans, Mice, Mice, Knockout, Nitric Oxide Synthase Type III, Placenta, Pregnancy, Uterus

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