Stephen Taylor

• M1-like monocytes are a major immunological determinant of severity in previously healthy adults with life-threatening influenza.

  Journal article

  Cole SL. et al, (2017), JCI Insight, 2

• Selective silencing of α-globin by the histone demethylase inhibitor IOX1: a potentially new pathway for treatment of β-thalassemia.

  Journal article

  Mettananda S. et al, (2017), Haematologica, 102, e80 - e84

• A molecular roadmap of definitive erythropoiesis from human induced pluripotent stem cells.

  Journal article

  Razaq MA. et al, (2017), Br J Haematol, 176, 971 - 983

• Suppression of the alternative lengthening of telomere pathway by the chromatin remodelling factor ATRX.

  Journal article

  Clynes D. et al, (2015), Nat Commun, 6

• Human induced pluripotent stem cell-derived B lymphocytes express sIgM and can be generated via a hemogenic endothelium intermediate.

  Journal article

  French A. et al, (2015), Stem Cells Dev, 24, 1082 - 1095

• Antibody-mediated complement C3b/iC3b binding to group B Streptococcus in paired mother and baby serum samples in a refugee population on the Thailand-Myanmar border.

  Journal article

  Herbert J. et al, (2015), Clin Vaccine Immunol, 22, 319 - 326

• DISTINCT PRO-INFLAMMATORY GENE EXPRESSION PROFILE IN MONOCYTES FROM SARCOIDOSIS PATIENTS WITH ACTIVE DISEASE

  Conference paper

  Crawshaw AP. et al, (2014), THORAX, 69, A88 - A88

• HTML5 PivotViewer: high-throughput visualization and querying of image data on the web.

  Journal article

  Taylor S. and Noble R., (2014), Bioinformatics, 30, 2691 - 2692

• Understanding functional miRNA-target interactions in vivo by site-specific genome engineering.

  Journal article

  Bassett AR. et al, (2014), Nat Commun, 5

• Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo.

  Journal article

  Woll PS. et al, (2014), Cancer Cell, 25, 794 - 808

• Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo

  Journal article

  Woll PS. et al, (2014), Cancer Cell, 25, 794 - 808

• Histamine enhances keratinocyte-mediated resolution of inflammation by promoting wound healing and response to infection

  Journal article

  Gutowska-Owsiak D. et al, (2014), BRITISH JOURNAL OF DERMATOLOGY, 170, E31 - E32

• Histamine enhances keratinocyte-mediated resolution of inflammation by promoting wound healing and response to infection.

  Journal article

  Gutowska-Owsiak D. et al, (2014), Clin Exp Dermatol, 39, 187 - 195

• Histamine enhances keratinocyte-mediated resolution of inflammation by promoting wound healing and response to infection

  Journal article

  Gutowska-Owsiak D. et al, (2014), Clinical and Experimental Dermatology, 39, 187 - 195

• Analysis of hundreds of cis-regulatory landscapes at high resolution in a single, high-throughput experiment.

  Journal article

  Hughes JR. et al, (2014), Nat Genet, 46, 205 - 212

• Histamine exerts multiple effects on expression of genes associated with epidermal barrier function.

  Journal article

  Gutowska-Owsiak D. et al, (2014), J Investig Allergol Clin Immunol, 24, 231 - 239

• ATRX dysfunction induces replication defects in primary mouse cells.

  Journal article

  Clynes D. et al, (2014), PLoS One, 9

• Dynamic analysis of gene expression and genome-wide transcription factor binding during lineage specification of multipotent progenitors

  Journal article

  May G. et al, (2013), Cell Stem Cell, 13, 754 - 768

• MIG: Multi-Image Genome viewer.

  Journal article

  McGowan SJ. et al, (2013), Bioinformatics, 29, 2477 - 2478

• Cellular interference in craniofrontonasal syndrome: males mosaic for mutations in the X-linked EFNB1 gene are more severely affected than true hemizygotes.

  Journal article

  Twigg SR. et al, (2013), Hum Mol Genet, 22, 1654 - 1662

• Reduced dosage of ERF causes complex craniosynostosis in humans and mice and links ERK1/2 signaling to regulation of osteogenesis

  Journal article

  Twigg SRF. et al, (2013), Nature Genetics, 45, 308 - 313

• Reduced dosage of ERF causes complex craniosynostosis in humans and mice and links ERK1/2 signaling to regulation of osteogenesis.

  Journal article

  Twigg SR. et al, (2013), Nat Genet, 45, 308 - 313

• Antigen-sensitive CD8 T-cell clones with tough HIV-1 suppression

  Conference paper

  Glanville JM. et al, (2013), LANCET, 381, 44 - 44

• Differentially expressed, variant U1 snRNAs regulate gene expression in human cells.

  Journal article

  O'Reilly D. et al, (2013), Genome Res, 23, 281 - 291

• High-resolution analysis of cis-acting regulatory networks at the α-globin locus

  Journal article

  Hughes JR. et al, (2013), Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 368

• High-resolution analysis of cis-acting regulatory networks at the α-globin locus.

  Journal article

  Hughes JR. et al, (2013), Philos Trans R Soc Lond B Biol Sci, 368

• Early dynamic fate changes in haemogenic endothelium characterized at the single-cell level.

  Journal article

  Swiers G. et al, (2013), Nat Commun, 4

• TNFα signals through specialized factories where responsive coding and miRNA genes are transcribed

  Journal article

  Papantonis A. et al, (2012), EMBO Journal, 31, 4404 - 4414

• TNFα signals through specialized factories where responsive coding and miRNA genes are transcribed.

  Journal article

  Papantonis A. et al, (2012), EMBO J, 31, 4404 - 4414

• Interleukin-17 mediates adhesion impairment in human keratinocytes - potential involvement in barrier dysfunction during atopic skin inflammation

  Conference paper

  Gutowska-Owsiak D. et al, (2012), ALLERGY, 67, 56 - 56

• Origins of paternal age effect mutations: frequent foci of abnormal signal activation in the testes of elderly men

  Conference paper

  Maher G. et al, (2012), JOURNAL OF MEDICAL GENETICS, 49, S86 - S86

• Smchd1-dependent and -independent pathways determine developmental dynamics of CpG island methylation on the inactive X chromosome.

  Journal article

  Gendrel AV. et al, (2012), Dev Cell, 23, 265 - 279

• Smchd1-Dependent and -Independent Pathways Determine Developmental Dynamics of CpG Island Methylation on the Inactive X Chromosome

  Journal article

  Gendrel AV. et al, (2012), Developmental Cell, 23, 265 - 279

• High frequency of HIV mutations associated with HLA-C suggests enhanced HLA-C-restricted CTL selective pressure associated with an AIDS-protective polymorphism.

  Journal article

  Blais ME. et al, (2012), J Immunol, 188, 4663 - 4670

• Intragenic enhancers act as alternative promoters.

  Journal article

  Kowalczyk MS. et al, (2012), Mol Cell, 45, 447 - 458

• RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3.

  Journal article

  Tavares L. et al, (2012), Cell, 148, 664 - 678

• RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3

  Journal article

  Tavares L. et al, (2012), Cell, 148, 664 - 678

• IL-17 downregulates filaggrin and affects keratinocyte expression of genes associated with cellular adhesion.

  Journal article

  Gutowska-Owsiak D. et al, (2012), Exp Dermatol, 21, 104 - 110

• The impact of HIV-1 infection and exposure on natural killer (NK) cell phenotype in Kenyan infants during the first year of life.

  Journal article

  Slyker JA. et al, (2012), Front Immunol, 3

• Selfish spermatogonial selection: evidence from an immunohistochemical screen in testes of elderly men.

  Journal article

  Lim J. et al, (2012), PLoS One, 7

• Discovering Regulatory SNPs by Genome-Wide Analysis of Differential Scl/TAL-1 Occupancy in Human Primary Erythroid Cells

  Conference paper

  De Gobbi M. et al, (2011), BLOOD, 118, 1450 - 1450

• Interleukin-22 downregulates filaggrin expression and affects expression of profilaggrin processing enzymes

  Journal article

  Gutowska-Owsiak D. et al, (2011), British Journal of Dermatology, 165, 492 - 498

• Interleukin-22 downregulates filaggrin expression and affects expression of profilaggrin processing enzymes.

  Journal article

  Gutowska-Owsiak D. et al, (2011), Br J Dermatol, 165, 492 - 498

• Genome sequence of Rhodobacter sphaeroides Strain WS8N.

  Journal article

  Porter SL. et al, (2011), J Bacteriol, 193, 4027 - 4028

• Generation of bivalent chromatin domains during cell fate decisions.

  Journal article

  De Gobbi M. et al, (2011), Epigenetics Chromatin, 4

• Interleukin-17 and interleukin-22 contribute to alterations in epidermal function via multiple pathways - role in atopic eczema

  Conference paper

  Gutowska-Owsiak D. et al, (2011), ALLERGY, 66, 19 - 19

• MicroRNA expression in multiple myeloma is associated with genetic subtype, isotype and survival.

  Journal article

  Chi J. et al, (2011), Biol Direct, 6

• IL-17 influences expression of genes associated with barrier function in keratinocytes

  Conference paper

  Gutowska-Owsiak D. et al, (2011), BRITISH JOURNAL OF DERMATOLOGY, 164, 906 - 906

• Global gene expression analysis of human erythroid progenitors

  Conference paper

  Merryweather-Clarke AT. et al, (2011), BRITISH JOURNAL OF HAEMATOLOGY, 153, 6 - 6

• Global gene expression analysis of human erythroid progenitors.

  Journal article

  Merryweather-Clarke AT. et al, (2011), Blood, 117, e96 - 108

• Phenotypic characterization of HIV-specific CD8+ T cells during early and chronic infant HIV-1 infection.

  Journal article

  Slyker JA. et al, (2011), PLoS One, 6

• IL-17A and IL-22 cause down-regulation of filaggrin - implications for the pathogenesis of atopic eczema

  Conference paper

  Gutowska-Owsiak D. et al, (2010), IMMUNOLOGY, 131, 43 - 43

• ATR-X syndrome protein targets tandem repeats and influences allele-specific expression in a size-dependent manner.

  Journal article

  Law MJ. et al, (2010), Cell, 143, 367 - 378

• MicroRNA expression in Sezary syndrome: identification, function, and diagnostic potential.

  Journal article

  Ballabio E. et al, (2010), Blood, 116, 1105 - 1113

• Genome-wide identification of TAL1's functional targets: insights into its mechanisms of action in primary erythroid cells.

  Journal article

  Kassouf MT. et al, (2010), Genome Res, 20, 1064 - 1083

• A small interfering RNA screen of genes involved in DNA repair identifies tumor-specific radiosensitization by POLQ knockdown.

  Journal article

  Higgins GS. et al, (2010), Cancer Res, 70, 2984 - 2993

• Ankylosing spondylitis monocytes show upregulation of proteins involved in inflammation and the ubiquitin proteasome pathway.

  Journal article

  Wright C. et al, (2009), Ann Rheum Dis, 68, 1626 - 1632

• Photoinduced, family-specific, site-selective cleavage of TIM-barrel proteins.

  Journal article

  Floyd N. et al, (2009), J Am Chem Soc, 131, 12518 - 12519

• Expression of microRNAs in diffuse large B cell lymphoma is associated with immunophenotype, survival and transformation from follicular lymphoma.

  Journal article

  Lawrie CH. et al, (2009), J Cell Mol Med, 13, 1248 - 1260

• Prioritizing genes of potential relevance to diseases affected by sex hormones: an example of myasthenia gravis.

  Journal article

  Kaur M. et al, (2008), BMC Genomics, 9

• Association between active genes occurs at nuclear speckles and is modulated by chromatin environment.

  Journal article

  Brown JM. et al, (2008), J Cell Biol, 182, 1083 - 1097

• Antigen Spondylitis monocytes show upregulation of proteins involved in antigen presentation

  Journal article

  Bowness P. et al, (2008), CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 26, 727 - 727

• CTAS - A CT score to quantify disease activity in pulmonary sarcoidosis

  Journal article

  Ho L., Thorax

Recent Publications

• M1-like monocytes are a major immunological determinant of severity in previously healthy adults with life-threatening influenza.

  Journal article

  Cole SL. et al, (2017), JCI Insight, 2

• Selective silencing of α-globin by the histone demethylase inhibitor IOX1: a potentially new pathway for treatment of β-thalassemia.

  Journal article

  Mettananda S. et al, (2017), Haematologica, 102, e80 - e84

• A molecular roadmap of definitive erythropoiesis from human induced pluripotent stem cells.

  Journal article

  Razaq MA. et al, (2017), Br J Haematol, 176, 971 - 983

• Suppression of the alternative lengthening of telomere pathway by the chromatin remodelling factor ATRX.

  Journal article

  Clynes D. et al, (2015), Nat Commun, 6

• Human induced pluripotent stem cell-derived B lymphocytes express sIgM and can be generated via a hemogenic endothelium intermediate.

  Journal article

  French A. et al, (2015), Stem Cells Dev, 24, 1082 - 1095