MRC WIMM Group Leader
My group provides computing support for bioinformatics analysis at the University of Oxford. We have expertise in many aspects of bioinformatics and especially encourage collaborations that require writing custom software, bioinformatics tools and databases. I co-developed Zegami, an image analysis and visualisation platform, which is now a Oxford spin-out company. I am currently researching the use of Virtual Reality in scientific visualisation.
Synergistic silencing of α-globin and induction of γ-globin by histone deacetylase inhibitor, vorinostat as a potential therapy for β-thalassaemia.
Mettananda S. et al, (2019), Sci Rep, 9
Low-Bias RNA Sequencing of the HIV-2 Genome from Blood Plasma.
James KL. et al, (2019), J Virol, 93
Reconstruction of the global neural crest gene regulatory network in vivo
Williams R. et al, (2018)
SCL/TAL1 cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells.
Chagraoui H. et al, (2018), Nat Commun, 9
Erythroferrone Inhibits the Induction of Hepcidin By BMP6
Arezes J. et al, (2018), BLOOD, 132