My research is associated with a programme of work to understand the role of individual genetic variation in determining blood cell traits and iron metabolism. Specifically, how these traits and mechanisms define the ability to donate blood, and the quality of red cells and other haematopoietic cells thus obtained.
The aim of the research programme is to understand the underlying genomic variations in different blood cell phenotypes and to identify changes in gene regulation in health and disease. This work encompasses functional studies on major erythroid, myeloid and lymphoid blood cell types to describe and better understand cellular and molecular mechanisms of blood related diseases.
I have previously worked in the field of Cardiovascular Medicine as well as Immunology and Endocrinology. One of the things that links all of these fields is the pursuit to understand the mechanisms of disease, more specifically, the signalling pathways behind them, to try and finds new targets for treatment which I would say defines me as a scientist.
I have a degree in Biochemistry from Lisbon University and did my PhD at the Brigham and Women's Hospital in Boston, USA. After moving to the UK I have been working in the Radcliffe Department of Medicine, currently as a Postdoctoral Researcher.