Myeloid leukemia in children 4 years or older with Down syndrome often lacks GATA1 mutation and cytogenetics and risk of relapse are more akin to sporadic AML.
Hasle H., Abrahamsson J., Arola M., Karow A., O'Marcaigh A., Reinhardt D., Webb DKH., van Wering E., Zeller B., Zwaan CM., Vyas P.