MA, MB BChir, MPhil (Cantab), DPhil (Oxon), MRCP
Senior Clinical Fellow in Electrophysiology
I was a British Heart Foundation funded Clinical Research Training Fellow investigating the role of Nitric Oxide Synthase 1 Adaptor Protein (NOS1AP) on cardiac repolarisation and arrhythmogenesis using a combination of in-vitro work and in-vivo physiological investigations. Training including skills in basic laboratory techniques (Western Blotting, q-PCR, NOS1 assays) as well as animal handling and in-vivo work (murine echocardiography, atrial fibrillation [AF] induction) to ex-vivo work (isolated heart VT stimulation, optical mapping). Also as part of my DPhil I diversified to investigate the causal relevance of ECG parameters on AF at a large population level, using genetic epidemiology techniques working in the Big Data Institute as part of the Nuffield Department of Population Health.
I won the European Society of Cardiology Young Investigator Award in Population Sciences for this work (Paris Congress, 2019) and successfully defended a DPhil entitled 'Understanding the role of NOS1AP on ECG parameters and arrhythmogenesis: insights from mice and men' supervised by Professor Barbara Casadei, Dr Jillian Simon and Professor Jemma C. Hopewell.
I completed my undergraduate and clinical training at Downing College, University of Cambridge and qualified in 2008. After doing Foundation Training in East Anglia, I was a Wellcome Trust funded Academic Clinical Fellow and completed an MPhil in Translational Medicine and Therapeutics from the University of Cambridge. I then became a Cardiology Registrar and after completing my core training have subspecialised in the field of Electrophysiology and Devices. I moved to the University of Oxford as a British Heart Foundation funded Clinical Research Training Fellow to pursue research as a DPhil student, before finishing my training and returning as a post-CCT Senior Clinical Fellow in Electrophysiology at the John Radcliffe alongside research commitments.
My research interests lie in translational electrophysiological research. In particular, I am interested in using insights from data from large populations to guide individualised therapies for arrhythmias.
First clinical use of novel ablation catheter incorporating local impedance data.
Martin CA. et al, (2018), J Cardiovasc Electrophysiol, 29, 1197 - 1206
Should Technical and Anatomical Difficulties Discourage Operators From Embarking on Transradial Access for Percutaneous Coronary Intervention?
Basavarajaiah S. et al, (2018), J Invasive Cardiol, 30, 341 - 347
Coarse fibrillatory waves in atrial fibrillation predict success of electrical cardioversion.
Zhao TX. et al, (2018), Ann Noninvasive Electrocardiol, 23
Improved outcome and cost effectiveness in ablation of persistent atrial fibrillation under general anaesthetic.
Martin CA. et al, (2018), Europace, 20, 935 - 942
Ablation of Complex Fractionated Electrograms Improves Outcome in Persistent Atrial Fibrillation of Over 2 Year's Duration.
Martin CA. et al, (2018), J Atr Fibrillation, 10