- Sparrow Group Research Group
Novo Nordisk Postdoctoral Research Fellow
- Stipendiary Lecturer, Merton College, Oxford
A novel approach to investigating how maternal diabetes contributes to congenital heart defects
I am a Novo Nordisk Postdoctoral Research Fellow in Dr Duncan Sparrow's group in the Department of Physiology, Anatomy and Genetics.
I studied neuroscience at the University of Bristol for my undergraduate degree and obtained my PhD from University College London in 2016, working on the anti-angiogenic therapy for diabetic retinopathy at the Institute of Ophthalmology. During this time, I also investigated the effects of VEGF splice variants in the treatment of diabetic neuropathy in collaboration with the University of Nottingham. In 2015 I was awarded the British Microcirculation Society Young Investigators Prize for my work on microvascular dysfunction in the diabetic retina.
In 2016 I was awarded a Novo Nordisk Postdoctoral Research Fellowship, investigating how pre-existing maternal diabetes induces embryonic heart defects with Dr Duncan Sparrow and Professor Dame Frances Ashcroft. I am also continuing research into how hyperglycaemia/hypoinsulinemia affects the retinal microvasculature.
Vascular endothelial growth factor-A 165 b ameliorates outer-retinal barrier and vascular dysfunction in the diabetic retina
Ved N. et al, (2017), Clinical Science, 131, 1225 - 1243
Vascular endothelial growth factor-A 165 b prevents diabetic neuropathic pain and sensory neuronal degeneration
Hulse RP. et al, (2015), Clinical Science, 129, 741 - 756
Noradrenaline-induced enhancement of oscillatory local field potentials in the mouse accessory olfactory bulb does not depend on disinhibition of mitral cells
Leszkowicz E. et al, (2012), European Journal of Neuroscience, 35, 1433 - 1445
Physiological role of vascular endothelial growth factors as homeostatic regulators
Bates DO. et al, Comprehensive Physiology
Congenital birth defects in embryos of diabetic mice
An E14.5 mouse embryo with pericardial oedema and exencephaly imaged using high resolution episcopic microscopy (HREM)