MSc (Hons) BSc (Hons)
- WIMM Graduate Student Association- Treasurer
- WIMM Women in Science Committee- Representative of WIMM Students
- Linacre College - President of Green Society
I am a DPhil student in Nerlov lab since April 2017. My work explores human haematopoietic stem cell (HSC) heterogeneity in adult BM with the aim of identifying gene signatures and surface markers that could allow identifying human HSC subsets with specific haematopoietic fate-restriction.
The human HSCs is the basis for the most common stem cell-based therapy in clinical practice, namely bone marrow transplantation. Improved understanding of human adult HSC biology will contribute to the treatment of both congenital and acquired blood disorders. In particular, better definition of human HSCs will facilitate efforts to genome edit human HSCs in congenital blood disorders, and improve donor selection for bone marrow transplantation.
Development of Small Molecule MEIS Inhibitors that modulate HSC activity.
Turan RD. et al, (2020), Sci Rep, 10
c-Myc inhibitor 10074-G5 induces murine and human hematopoietic stem and progenitor cell expansion and HDR modulator Rad51 expression.
Aksoz M. et al, (2018), Curr Cancer Drug Targets
Identification of cardiogenic factors modulated during neonatal cardiac regeneration
Kocabas F. et al, (2018), CARDIOVASCULAR RESEARCH, 114, S16 - S16
Emerging Roles of Meis1 in Cardiac Regeneration, Stem Cells and Cancer.
Aksoz M. et al, (2018), Curr Drug Targets, 19, 181 - 190