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Lisa Ayers

BSc (Hons), MSc, PhD, CSci

Postodoctoral Research Fellow

Following training as a Clinical Scientist in Immunology at the Oxford University Hospitals NHS Trust, I undertook a PhD funded by the NIHR, which focused on the optimisation of microvesicle detection and the investigation of extracellular vesicles in obstructive sleep apnoea preeclampsia. My thesis was entitled 'Circulating cell derived microparticles potential biomarkers of cardiovascular risk'. I am currently funded by an NIHR Healthcare Science Postdoctoral Fellowship to investigate the dynamic release and clearance of cell-derived microparticles during acute cardiac stress in coronary artery disease patients and healthy individuals, in collaboration with the Cardiovascular Clinical Research Facility, University of Oxford. 

The research conducted during this Fellowship has identified several potential areas of improvement in the diagnosis and monitoring of patients with suspected coronary artery disease, early hypertension and pregnancy related hypertension. These patients have increased long-term risks of future cardiovascular disease with significant co-morbidities. Therefore early identification and intervention for these patients could be of great benefit to these patients and potentially save significant costs to the NHS. In addition, I am interested in the translation and validation of cellular and molecular research assays into clinically useful diagnostic tests, specifically for patients with cardiovascular disease, primary antibody deficiency, autoimmunity and allergy. As a Clinical Academic I have maintained my clinical skills and I recently obtained Associate membership of the Royal College of Pathologists through examination. In 2016 I was awarded the Chief Scientific Officer Healthcare Scientist Rising Star award for my research achievements and my role supporting other Clinical Academics.