JDRF Research Fellow
I joined the Oxford Centre for Diabetes, Endocrinology & Metabolism (OCDEM) as a JDRF-funded Research Fellow in 2016. My research interests are centred on the early development of autoimmunity in type 1 diabetes and the factors triggering progression to clinical disease. During my postdoctoral studies, we identified a major target of the autoimmune response in diabetes, a protein called tetraspanin-7. My current project aims to characterise the immune response to tetraspanin-7 in people with diabetes and to further our understanding of the role of this protein in the insulin-producing beta cell.
Islet Autoantibody Standardization Program 2018 Workshop: Interlaboratory Comparison of Glutamic Acid Decarboxylase Autoantibody Assay Performance.
Lampasona V. et al, (2019), Clin Chem, 65, 1141 - 1152
Utility of anti-tetraspanin 7 auto-antibodies in adults and children with type 1 diabetes: insights from the ADDRESS-2 study
Groom O. et al, (2019), DIABETOLOGIA, 62, S204 - S205
A longitudinal study of autoantibodies against cytochrome P450 side-chain cleavage enzyme in dogs (Canis lupus familiaris) affected with hypoadrenocorticism (Addison's disease).
Boag AM. et al, (2018), Vet Immunol Immunopathol, 202, 41 - 45
Autoantibody reactivity to tetraspanin-7 is directed to the cytoplasmic domains: Implications for immunoassay design
Mclaughlin KA. et al, (2018), DIABETIC MEDICINE, 35, 67 - 67
High frequency of antibodies to IA-2, but lower frequencies of GAD65, ZnT8 and Tspan7 antibodies, in Asian patients with Type 1 diabetes
Tombs M. et al, (2018), DIABETIC MEDICINE, 35, 66 - 67