Imaging Methods: Magnetic Resonance Imaging.

Thomas KE., Fotaki A., Botnar RM., Ferreira VM.

Myocardial inflammation occurs following activation of the cardiac immune system, producing characteristic changes in the myocardial tissue. Cardiovascular magnetic resonance is the non-invasive imaging gold standard for myocardial tissue characterization, and is able to detect image signal changes that may occur resulting from inflammation, including edema, hyperemia, capillary leak, necrosis, and fibrosis. Conventional cardiovascular magnetic resonance for the detection of myocardial inflammation and its sequela include T2-weighted imaging, parametric T1- and T2-mapping, and gadolinium-based contrast-enhanced imaging. Emerging techniques seek to image several parameters simultaneously for myocardial tissue characterization, and to depict subtle immune-mediated changes, such as immune cell activity in the myocardium and cardiac cell metabolism. This review article outlines the underlying principles of current and emerging cardiovascular magnetic resonance methods for imaging myocardial inflammation.

DOI

10.1161/CIRCIMAGING.122.014068

Type

Journal article

Publication Date

2023-01-01T00:00:00+00:00

Volume

16

Keywords

cardiac imaging techniques, immune system, inflammation, magnetic resonance imaging, Humans, Contrast Media, Magnetic Resonance Imaging, Myocardium, Myocarditis, Inflammation, Magnetic Resonance Imaging, Cine, Predictive Value of Tests

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