DPHIL SUPERVISOR PROFILE
Associate Professor of Cardiovascular Science
Large studies linking common variations to the occurrence of coronary artery disease have enabled us to identify several new genes that may have a causative influence on the susceptibility to developing coronary artery disease. However, for many of these genes the mechanism by which they alter cardiovascular disease pathology is unknown.
Crucial functions of alpha-actinin 2 in the embryonic heart
Gehmlich K. et al, (2022), CARDIOVASCULAR RESEARCH, 118
PHACTR1 modulates vascular compliance but not endothelial function: a translational study.
Wood A. et al, (2022), Cardiovasc Res
Endothelial GTPCH (GTP Cyclohydrolase 1) and Tetrahydrobiopterin Regulate Gestational Blood Pressure, Uteroplacental Remodeling, and Fetal Growth.
Chuaiphichai S. et al, (2021), Hypertension
Developmental role of PHD2 in the pathogenesis of pseudohypoxic pheochromocytoma.
Eckardt L. et al, (2021), Endocr Relat Cancer, 28, 757 - 772
A key role for the novel coronary artery disease gene JCAD in atherosclerosis via shear stress mechanotransduction.
Douglas G. et al, (2020), Cardiovasc Res, 116, 1863 - 1874