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Cheryl Tan

BSc(Hons), MRes, DPhil

Postdoctoral Researcher

Born and raised in Singapore, I was awarded a scholarship to complete a one year accelerated A levels program in the United Kingdom. I later completed my undergraduate degree in Biological Sciences and subsequently, a Master of Research in Reproduction and Pregnancy at the University of Manchester. My MRes research focused on the effects of manipulating hexosamine biosynthesis pathway on embryonic implantation and invasion. Following this, I was appointed as a research project officer at the National Technological University, Singapore, where I investigated the roles of histone methyltransferase enhancer of zeste homolog 2 (EZH2) in cerebellum ataxia.

I returned to the UK on a sponsored scholarship to pursue a DPhil in Cardiovascular Medicine under the supervision of Prof. Paul Lesson, Assoc Prof. Adam Lewandowski and, Assoc. Prof. Mariane Bertagnolli. My DPhil research focused on a unique population of endothelial progenitor cells - endothelial colony-forming cells, to investigate underlying mechanisms for cardiovascular disease development in young adults of different birth histories and varying blood pressure profiles.

I am an investigator on the TEPHRA (Trial of Exercise to Prevent HypeRtension in young Adults), the CHAPTER (Cardiovascular Health Assessment of Preterm and TERm-born children), CAREFOL-HT (Clinical Antenatal Randomised study to CharactErise key roles of TetrahydroFOLate in HyperTensive Pregnancies) and POP-HT (Physician Optimised Post-partum Hypertension Treatment) studies.

I have a general interest in endothelial cell function and microvascular remodelling during and after hypertensive pregnancies. I also have a strong interest in the generation of functional 3D organoids and microtissue. 

'The Growing Heart- From mother to offspring' For Oxford BHF CRE Symposium Bench to Bedside Research - Image Competition 2021

© Cheryl Tan
A winning image for Oxford BHF CRE Symposium Bench to Bedside Research - Image Competition 2021. This image reflects the complex cardiac developmental process of the offspring that begins during gestation.

'The Heart and Brain Axis' for British Heart Foundation Reflections of Research image competition 2019

"The image that won the hearts and minds of our supporters was a team effort from Cheryl Tan, Maryam Alsharqi, Dr Winok Lapidaire, Dr Mariane Bertagnolli and Dr Adam Lewandowski, all based at the Radcliffe Department of Medicine’s Oxford Cardiovascular Clinical Research Facility (CCRF) at the University of Oxford. This image reflects the complex interaction between the heart and the brain, portraying some of the different imaging techniques that they use to investigate this relationship. These include magnetic resonance imaging of the heart and brain, ultrasound imaging of the heart, and fluorescent imaging of the heart and blood vessel cells." - The British Heart Foundation