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Adjunct Member - Oxford Ludwig Institute for Cancer Research

Oxford Ludwig

Bethan Psaila


Associate Professor of Haematology

  • Cancer Research UK Advanced Clinician Scientist

Clinician Scientist and Group Leader, MRC Weatherall Institute of Molecular Medicine

Our research focuses on four key areas: (1) Dissecting the interactions between blood stem cells, megakaryocytes and the stroma in normal haematopoiesis and blood malignancies; (2) Development and application of human bone marrow organoids to study normal and malignant haematopoiesis and validate targets in the relevant tissue microenvironment; (3) Developing novel strategies to selectively target cancer stem cells and pathological megakaryocytes in myelofibrosis, a severe bone marrow malignancy; (4) Understanding our recent discovery that platelets contain a repertoire of DNA fragments sequestered from cell free DNA, and confirming clinical utility for cancer detection and for pre-natal diagnosis.

In the clinic, I care for patients with myeloproliferative neoplasms, leading a small portfolio of clinical trials with a focus on immunotherapies am Deputy Chair of the National Cancer Research (NCRI) Haematology-Oncology MPN Subgroup and actively contribute to local and national treatment guidelines, patient forums and priority setting workshop. 

I trained at Clare College, Cambridge, Imperial College London/The Hammersmith Hospital, Cornell, New York, and the National Institutes of Health, Bethesda USA.

I am also a Senior Fellow of New College, Oxford, recruiting and overseeing clinical training of ~20-30 medical students per year. 

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