Unusual nucleic acids activate innate immunity and may be present in transformed cells. Meng et al. (2021) find that cancer-associated mutations in NF2 turn this tumor suppressor into a potent antagonist of DNA- and RNA-induced innate immune signaling.
Journal article
2021-10-21T00:00:00+00:00
81
4109 - 4110
1
Immunity, Innate, Interferons, Nucleic Acids, RNA, Signal Transduction