My work has been in sequence analysis, spanning from building families of protein domains to comparative genomics and Next-generation sequencing analysis.
UMI-tools: modeling sequencing errors in Unique Molecular Identifiers to improve quantification accuracy.
Smith T. et al, (2017), Genome Res, 27, 491 - 499
11β-hydroxysteroid dehydrogenase-1 deficiency alters the gut microbiome response to Western diet.
Johnson JS. et al, (2017), J Endocrinol, 232, 273 - 283
Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson's disease.
Sandor C. et al, (2017), Hum Mol Genet, 26, 552 - 566
Defining the microbial transcriptional response to colitis through integrated host and microbiome profiling.
Ilott NE. et al, (2016), ISME J, 10, 2389 - 2404
High-fat diet disrupts metabolism in two generations of rats in a parent-of-origin specific manner.
Chambers TJG. et al, (2016), Sci Rep, 6