TREM-like transcript 1: a more sensitive marker of platelet activation than P-selectin in humans and mice.

Smith CW., Raslan Z., Parfitt L., Khan AO., Patel P., Senis YA., Mazharian A.

Platelet activation in vitro results in a more rapid and greater upregulation of TLT-1 surface expression compared with P-selectin. TLT-1 is more rapidly translocated to the surface of activated platelets than P-selectin during thrombus formation in vivo.

DOI

10.1182/bloodadvances.2018017756

Type

Journal article

Publication Date

2018-08-28T00:00:00+00:00

Volume

2

Pages

2072 - 2078

Total pages

6

Keywords

Animals, Biomarkers, Blood Platelets, Humans, Mice, P-Selectin, Platelet Activation, Receptors, Immunologic

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