Researchers at the MRC Weatherall Institute of Molecular Medicine have developed the first combined human bone and bone marrow organoid platform capable of modelling long term blood and immune cell production in a fully human 3D system.
A new study led by researchers at the MRC Molecular Haematology Unit has shown that resistance to a targeted treatment for acute myeloid leukaemia (AML) can develop much earlier than expected.
New research shows that iron from supplements and fortified foods is well-absorbed in children living with virally suppressed HIV, and that administering iron supplements with prebiotics may enhance their effectiveness and improve their safety.
Researchers at the MRC Translational Immune Discovery Unit have identified how rare populations of abnormal cells drive the formation and persistence of fistulas - painful, tunnel-like tracts that develop in around 30% of people with Crohn\u2019s disease - paving the way for targeted treatments.
RDM scientists have achieved the most detailed view yet of how DNA folds and functions inside living cells, revealing the physical structures that control when and how genes are switched on.
Congratulations are in order for Dr Abdullah (Abs) Khan, who has been awarded a Wellcome Career Development Award for his research on age-related immune dysfunction using human model systems.
From 29 September to 1 October 2025, researchers from across the world gathered in Oxford for a unique conference and hackathon exploring how advances in artificial intelligence can deepen understanding of T-cell biology.
Oxford scientists build a connected, \u2018multi-organoid\u2019 platform that recreates immune recruitment to the heart, opening new avenues to probe disease and test therapies.
Earlier this year, a group of researchers from the MRC Weatherall Institute of Molecular Medicine attended the Big Bang Fair in Birmingham, showcasing medical research through a series of hands-on activities.
Study led by Psaila Group uncovers previously unknown function of platelets as DNA \u2018vacuum cleaners\u2019 in the blood, with profound implications for cancer diagnosis and prenatal screening.
Claus Nerlov, Professor of Stem Cell Biology, has been awarded funding from Wellcome to map the gene regulatory networks in blood cell production and seek new therapeutic targets.
The latest study from researchers in the MRC Translational Immune Discovery Unit in the MRC Weatherall Institute of Molecular Medicine has been published in Cell Reports Medicine.
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